GMP Certified Cefoperazone Sodium for Injection / Cefoperazone Injection

• Application: Internal Medicine
• Usage Mode: Injection
• Suitable for: Elderly, Children, Adult
• State: Solid
• Shape: Powder
• Type: Inorganic Chemicals
• Model NO.: CSI
• Pharmaceutical Technology: Chemical Synthesis
• Drug Reg./Approval No.: Available
• Drug Ad Approval No.: Available
• OEM: Available
• GMP: Available
• Transport Package: Vial + Box
• Specification: 0.5g, 1g, 2g, 3g, 4g
• Trademark: Fraken
• Origin: China
• HS Code: 3004201800
• Production Capacity: 100000vials/Month

Product Description

Cefoperazone Sodium For Injection
Cefoperazone sodium is a semisynthetic broad-spectrum cephalosporin antibiotic for parenteral use only. Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. 
 

1. Content:	500mg, 1g, 1.5g, 2g, 3g, 4g
2. Packaging:	10vials x 100boxes 50Vials × 20Boxes
3. Indications:	Cefoperazone is indicated for the treatment of the following infections: 1) Respiratory tract infections caused by S. pneumoniae, H. influenzae, S. aureus (penicillinase and non-penicillinase producing strains), S. pyogenes (Group A beta-hemolytic streptococci), P. aeruginosa, Klebsiella pneumoniae, E. coli, Proteus mirabilis, and Enterobacter species. 2) Peritonitis and other intra-abdominal infections caused by E. coli, P. aeruginosa, and anaerobic gram-negative bacilli (including Bacteroides fragilis). 3) Bacterial septicemia caused by S. pneumoniae, S. agalactiae, S. aureus, Pseudomonas aeruginosa, E. coli, Klebsiella spp., Klebsiella pneumoniae, Proteus species (indole-positive and indole-negative), Clostridium spp. and anaerobic gram-positive cocci. 4) Infections of the skin and skin structures caused by S. aureus (penicillinase and non-penicillinase producing strains), S. pyogenes, and P. aeruginosa. 5) Pelvic Inflammatory Disease, Endometritis, and Other Infections of the Female Genital Tract caused by N. gonorrhoeae, S. epidermidis, S. agalactiae, E. coli, Clostridium spp., Bacteroides species (including Bacteroides fragilis), and anaerobic gram-positive cocci. 6) Urinary tract infections caused by Escherichia coli and Pseudomonas aeruginosa. 7) Enterococcal Infections. Although cefoperazone has been shown to be clinically effective in the treatment of infections caused by enterococci in cases of peritonitis and other intra-abdominal infections, infections of the skin and skin structures, pelvic inflammatory disease, endometritis and other infections of the female genital tract, and urinary tract infections, the majority of clinical isolates of enterococci tested are not susceptible to cefoperazone but fall just at or in the intermediate zone of susceptibility, and are moderately resistant to cefoperazone. However, in vitro susceptibility testing may not correlate directly with in vivo results. Despite this, cefoperazone therapy has resulted in clinical cures of enterococcal infections, chiefly in polymicrobial infections. Cefoperazone should be used in enterococcal infections with care and at doses that achieve satisfactory serum levels of cefoperazone.

Cefoperazone Sodium and Sulbactam Sodium for Injection

1:1	1500mg	750mg+750mg
	3.0g	1.5g+1.5g
	4.0g	2.0g+2.0g
	2.0g	1.0g+1.0g
	500mg	250mg+250mg
	1.0g	0.5g+0.5g
2:1	3.0g	2.0g+1.0g
	1.5g	1.0g+0.5g
	750mg	500mg+250mg

Cefoperazone sodium I.P. / Sulbactam sodium I.P. combination is available as a dry powder for reconstitution in a 1:1 and 2:1 ratio in terms of free Sulbactam /Cefoperazone. 
Cefoperazone sodium I.P. is a semisynthetic broad-spectrum cephalosporin antibiotic for parenteral use only. It contains 34 mg sodium (1.5 mEq) per gram. Cefoperazone is a white crystalline powder which is freely soluble in water. The molecular weight is 667.65.
Sulbactam sodium I.P. is a derivative of the basic penicillin nucleus. It is an irreversible beta-lactamase inhibitor for parenteral use only. Chemically it is sodium penicillinate sulfone. It contains 92 mg sodium (4 mEq) per gram. Sulbactam is an off-white crystalline powder which is highly soluble in water. The molecular weight is 255.22.

DOSAGE FORM AND STRENGTH
Vials of the 1:1 product contain the equivalent of 500 mg + 500 mg and 1000 mg + 1000 mg of cefoperazone and sulbactam, respectively.
Vials of the 2:1 product contain the equivalent of 1000 mg + 500 mg and  2000 mg + 1000 mg of cefoperazone and sulbactam, respectively.
 
Product list:

Cefradine for Injection	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Cefazolin Sodium for Injection	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Cefoperazone Sodium and Sulbactam Sodium for Inj.	1.0g/1.5g/2.0g	1/10/50vial/box,600/1000vial/carton	USP
Cefoperazone Sodium for Inj.	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Ceftriaxone Sodium for Injection	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Cefotaxime Sodium for Injection	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Ceftazidime for Injection	0.25g/0.5g/1.0g	1/10/50vial/box,600/1000vial/carton	USP
Cefepime for injection	0.5g/1g	1/10/50vial/box,600/1000vial/carton	USP
Cefalotin Sodium for Inj	0.5g/1g	1/10/50vial/box,600/1000vial/carton	USP
Cefuroxime for injection	0.75g/1.5g	1/10/50vial/box,600/1000vial/carton	USP