L-Alpha Glycerylphosphorylcholine (Alpha GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease and is used as a nootropic dietary supplement to enhance memory and cognition.
L-α-glycerophosphatidylcholine (GPC) is the simplest phospholipid, and an intermediate metabolite in the choline pathway. In addition, GPC serves as an organic osmolyte in the kidney and may play a role in sperm motility. In diet, it is normally presented in low amounts.
Other name: 2,3-Dihydroxypropyl 2-trimethylazaniumylethyl phosphate;2-(((2,3-Dihydroxypropoxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium inner salt
CAS NO.: 28319-77-9
EINECS NO.: 248-962-2
MF: C8H20NO6P
MW: 257.22
Appearance: white powder
Specification: 50%,85%,98%
Specification:
Test items |
Specification |
Description |
White powder,Neutral odor, very highly hygroscopic |
Identification(NMR) |
Conforms to the standard |
Solubility(H2O, 10% w/v) |
Clear |
Bulk Density (Untapped) |
0.90g/cm3~1.08g/cm3 |
Stability |
Dry and light protected storage |
Color of solution |
≤Y7 |
Water content |
≤2.0% |
pH |
7.5~9.0 |
Specific Rotation[α]25D |
-2.4O~2.95O |
Related Substances (HPLC) |
G.P.E. :<0.2% |
Related Substances(TLC) |
Single spot |
Purity(by Titration)L-α-Glycerophosphoryl Choline |
≥99.0% |
Solvents Residue(Ethanols) |
≤1.0% |
Function:
1. Increase human Growth
2. Improve mental focus and cognitive function.
3. Improve strengh.
Type:
1. L-alpha-Glyceryl phosphoryl choline (GPC )50%
2. L-alpha-Glyceryl phosphoryl choline (GPC )85%
3. L-alpha-Glyceryl phosphoryl choline (GPC )99%
4. L-alpha-Glyceryl phosphoryl choline (GPC )Liquid
5. L-alpha-Glyceryl phosphoryl choline (GPC )40%
Applications:
Alpha GPC 28319-77-9 rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.Alpha GPC is derived from highly purified soy lecithin by companies like Lipoid, VAV Life Sciences, Chemi SPA etc.
Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's Disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.
Commonly used doses are 300-1,200 mg daily.
Competitive Advantage:
1. High purity
2. Low impurity
3. Low residual solvent
4. Good quality control
5. High stability
6. High output with low price
7. Prompt Shipping
Package: As your request.
Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life: Two years when properly stored.
Delivery: Within one or two months after receiving your prepayment.
Service we can provide:
1. Mixed container, we can mix different items in one container.
2. Quality control, before shipment, free sample for test. After shipment, keep sample for 3 years
3. Prompt shipment with professional documents
4. Packing as your request, with photo before shipment.
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Mr. Liu
Qingdao fraken international trading Co., Ltd
Address: RM1005 post mansion yan'an three road, qingdao, China
Tel: 0086 532 83899718
Fax: 0086 532 83623236
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