| Customization: | Available |
|---|---|
| CAS No.: | 9003-98-9 |
| Formula: | Available |
|
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Source: Bovine Pancrease
EC: 3.1.21.1
DESCRIPTION
Bovine pancreatic deoxyribonuclease (DNase) is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with free hydroxyl group at the 3' position and phosphate group at the 5' position. The optimum pH is 7.8. DNase I is activated by bivalent metals, and inhibited by chelating agents such EDTA and sodium dodecyl sulfate. DNase I can be stabilized against proteolytic digestion by 5 mM Ca2+.
Deoxyribonuclease has been chromatographically purified to remove trace contaminating proteases. DNase may be used in clinic to thin and liquefy mucus in the lungs.
Other name: Alkaline DNase;Alkaline deoxyribonuclease;DNA depolymerase;DNA endonuclease;DNA nuclease;DNAase;DNase;Deoxyribonuclease A;Deoxyribonuclease I;Deoxyribonucleic phosphatase;Desoxyribonuclease;Dornase;Pancreatic deoxyribonuclease;Pancreatic dornase
CAS NO.: 9003-98-9
EINECS NO.: 232-667-0
Appearance:white crystalline powder
Specification:99%min
Standard: EP/BP/USP
Odor: odorless
SPECIFICATION (I)
|
Item |
Specifications |
Methods |
|
Appearance |
White or pale yellow lyophilized powder |
|
|
Activity |
≥ 3,000 Christensen units/mg powder |
K.P. |
|
Loss on drying |
≤ 0.3% |
K.P. |
|
Residue on ignition |
≤ 1.0% |
K.P. |
Conclusion: Product complies with KP.
SPECIFICATION (II)
|
Activity |
≥ 500 Kunitz units/mg powder |
Sigma-aldrich |
SPECIFICATION (III)
|
Activity |
≥ 2,000 Kunitz units/mg powder |
Sigma-aldrich |
Packing:as your request.
Storage Situation: Store in an airtight container, at a temperature of 2°C to 8°C.
Shelf Life: Two years when properly stored.
Delivery: within two weeks after receiving your prepayment.
Hyaluronidase, HAase
Source: mammalian testes
EC: 3.2.1.35
DESCRIPTION
Hyaluronidase is a glycoprotein containing 5% mannose and 2.7% glucosamine. Optimum pH range is 4.5-6.0. The enzyme catalyzes the hydrolysis of endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfate A and C (but not B), primarily to tetrasaccharide residues.
Hyaluronidase is extracted from bovine testes, and has been chromatographically purified to remove trace contaminating proteases.
SPECIFICATION
|
Item |
Specification |
Method |
|
[Appearance] |
A white or yellowis-white powder |
|
|
[Identification] |
Complies |
EP |
|
pH |
4.5 - 7.5 |
EP |
|
Appearance of solution |
Clear |
EP |
|
Loss on drying |
≤ 5.0% |
EP |
|
Bacterial endotoxins |
Less than 0.2 IU per IU of hyaluronidase |
EP |
|
Limit of tyrosine |
≤ 0.25 μg per USP Hyaluronidase U. |
USP |
|
Activity |
≥ 300 IU/mg powder |
EP |
Conclusion: Product complies with USP and EP.
Packing: as your request.
Storage Situation: Store in an airtight container, at a temperature of 2°C to 8°C.
Shelf Life: Two years when properly stored.
Delivery: within two weeks after receiving your prepayment.
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