Rutin is extract from Flos Sophorae lmmaturus. Its standards are as follows:
1. NF11
2. DAB9
3. DAB10
Rutin, also called rutoside, quercetin-3-O-rutinoside, rutoside trihydrate and sophorin, is the glycoside between the flavonol quercetin and the disaccharide rutinose (α -L-rhamnopyranosyl-(1→6))-β -D-glucopyranose). In the fava d'anta tree, the synthesis is done via a rutin synthase activity. Rutin (quercetin rutinoside), like quercitrin, is a glycoside of the flavonoid quercetin. As such, the chemical structures of both are very similar, with the difference existing in the hydroxyl functional group. Both quercetin and rutin are used in many countries as medications for blood vessel protection, and are ingredients of numerous multivitamin preparations and herbal remedies.
Rutin is one of the phenolic compounds found in the invasive plant species Carpobrotus edulis and contributes to the antibacterial and antioxidant properties of the plant. Its name comes from the name of Ruta graveolens, a plant that also contains rutin.
Troxerutin is DAB1999.
Troxerutin is a derivative of the natural bioflavonoid rutin. Troxerutin is found in many plants, and can be easily extracted from Sophora japonica (Japanese pagoda tree). Troxerutin is best suited for the treatment of the pre-varicose and varicose syndrome, varicose ulcers, trombophlebitis, post-phlebitic conditions, chronic venous deficiency, and hemorrhoids. Troxerutin can also be successfully applied for muscle pain and edemas due to traumatic vein blood-flow disorders and hematomes.
Quercetin: 95-102%
Quercetin is a type of plant-based chemical, or phytochemical, known as a flavonoid (see also Phytochemicals). Good sources include apples, onions, teas, red wines, and many other foods. Quercetin is also available as a dietary supplement.
Quercetin appears to have anti-inflammatory and antioxidant properties. It has been promoted as being effective against a wide variety of diseases, including cancer. While some early lab results appear promising, as of yet there is no reliable clinical evidence that quercetin can prevent or treat cancer in humans.
Dihydroquercetin: 90-95%
L(+)-Rhamnose, L-(+)-Rhamnose Monohydrate, L-rhamnose monohydrate, L-rhamnose
1. Source: Sophora Japonica Flos.
2. CAS No.: 3615-41-6
3. Content: 98% min.
Appearance: White fine powder
We can also supply Flos Sophorae lmmaturus. It is also flower-bud of Sophora japonica linn.
| Items of Rutin |
Standards |
Results |
| Description |
Greenish-yellow Powder |
Complies |
| Assay |
≥95% |
95.86% |
| Mesh Size |
100%pass 80mesh |
Complies |
| Ash Content |
≤5.0% |
0.28% |
| Loss on Drying |
5.5-9.0% |
7.2% |
| Heavy Metal |
≤20ppm |
Complies |
| Red pigment |
≤0.004% |
Complies |
| Green pigment |
≤0.004% |
Complies |
| Quercetin |
≤3.0% |
<0.1% |
| Isoquercitrin |
≤3.5% |
Complies |
| As |
≤2ppm |
Complies |
| Pb |
≤2ppm |
Complies |
| Total Plate Count |
≤1000cfu/gm |
Complies |
| Yeast&Mold |
≤100cfu/gm |
Complies |
| E.coil |
Negative |
Negative |
| Salmonella |
Negative |
Negative |
| Items of Troxerutin |
Specification |
Result |
| Characters |
| Appearance |
yellowish-green, crystalline powder, hygroscopic |
Complies |
Solubility
|
Free soluble in water |
Complies |
| Slightly soluble in 96% ethanol |
Complies |
| Practically insoluble in methylene chloride |
Complies |
| Identification |
| Method A |
IR absorption(EP7.0 2.2.24) |
Complies |
| Method B |
HPLC chromatograms(obtained in test) |
Complies |
| Tests |
| Composition(EP7.0 2.2.29) |
Principal peak ≥ 80% |
81.99% |
| Other peak ≤ 5 %,except only one peak ≤ 10% |
Complies |
| Ethylene oxide((EP7.0 2.2.28) |
≤ 1ppm |
Complies |
| Heavy metals(EP7.0 2.4.8) |
≤ 20ppm |
Complies |
| Loss on drying (EP7.0 2.2.32) |
≤ 5.0% |
3.47% |
| Sulphated ash(EP7.0 2.4.14) |
≤ 0.4% |
0.09% |
| Methanol(EP7.0 2.2.28) |
≤ 3000ppm |
1944.2ppm |
| Assay (anhydrous substance) UV (EP7.0 2.2.25) |
95.0-105.0% |
98.51% |
| Microbiological test |
| Total plate count |
≤ 1000CFU/g |
<10 CFU/g |
| Yeast & Mould |
≤ 100CFU/g |
<10 CFU/g |
| E.Coli |
Absent |
ND |
| Pseudomonas aeruginosa |
Absent |
ND |
| Conclusion: The test results conform to EP7.0 |
| Storage: In an airtight container,protected from light |
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