GMP Certified Galantamine Hydrobromide Sustained-Release Tablets
|FOB Price:||US $100 / Box|
|Min. Order:||100 Boxes|
|Min. Order||FOB Price|
|100 Boxes||US $100/ Box|
|Production Capacity:||10000carton Per Month|
|Payment Terms:||L/C, T/T, Money Gram, Western Union|
- Model NO.: GLT HBr
- Pharmaceutical Technology: Chemical Synthesis
- Form: Tablets
- Specification: GMP, USP
- Type: Inorganic Chemicals
- Color: White
- Trademark: Fraken
- Origin: China
Galantamine hydrobromide is a reversible, competitive acetylcholinesterase inhibitor. Galantamine hydrobromide is known chemically as (4aS, 6R, 8aS)-4a, 5, 9, 10, 11, 12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a, 3, 2-ef]benzazepin-6-ol hydrobromide. It has an empirical formula of C17H21NO3? HBr and a molecular weight of 368.27. Galantamine hydrobromide is a white to almost white powder and is sparingly soluble in water.
Galantamine hydrobromide is indicated for the treatment of mild to moderate dementia of the Alzheimer's type.
The dosage of galantamine tablets shown to be effective in controlled clinical trials is 16-32 mg/day given as twice daily dosing. As the dose of 32 mg/day is less well tolerated than lower doses and does not provide increased effectiveness, the recommended dose range is 16-24 mg/day given in a BID regimen. The dose of 24 mg/day did not provide a statistically significant greater clinical benefit than 16 mg/day. It is possible, however, that a daily dose of 24 mg of galantamine might provide additional benefit for some patients.
The recommended starting dose of galantamine tablets and Oral Solution is 4 mg twice a day (8 mg/day). The dose should be increased to the initial maintenance dose of 8 mg twice a day (16 mg/day) after a minimum of 4 weeks. A further increase to 12 mg twice a day (24 mg/day) should be attempted after a minimum of 4 weeks at 8 mg twice a day (16 mg/day). Dose increases should be based upon assessment of clinical benefit and tolerability of the previous dose.
Galantamine tablets should be administered twice a day, preferably with morning and evening meals.