Gastrodin
Chemical Name: 4-(hydroxymethyl) phenyl- β -D-Glucopyranoside
Molecular formula: C13H18O7
Molecular weight: 286.28
Characters: A white needle crystal, melting point: 154~155º C. Soluble in water, methanol, ethanol, not
Soluble in chloroform and ether.
Therapeutic indications: Gastrodin is extracted from Rhizoma gastrodiae and effective in tranquilizing and
Allaying excitement, anti-vertigo, improving sleeping, and helping strengthen immune response.
Package: 1kg per bag, 15kg/tin, 50kg/drum
Gastrodin is a natural phenol. It is the glucoside of 4-hydroxybenzyl alcohol (gastrodigenin). It can be isolated from the orchids Gastrodia elata or from the rhizome of Galeola faberi.
It can also be produced by biotransformation of 4-hydroxybenzaldehyde by Datura tatula cell cultures.
Gastrodin, an active component of tall gastrodia tuber, is widely used in the treatment of dizziness, paralysis, epilepsy, stroke and dementia, and exhibits a neuroprotective effect. A rat model of spinal cord injury was established using Allen's method, and gastrodin was administered via the subarachnoid cavity and by intraperitoneal injection for 7 days. Results show that gastrodin promoted the secretion of brain-derived neurotrophic factor in rats with spinal cord injury. After gastrodin treatment, the maximum angle of the inclined plane test, and the Basso, Beattie and Bresnahan scores increased. Moreover, gastrodin improved neural tissue recovery in the injured spinal cord. These results demonstrate that gastrodin promotes the secretion of brain-derived neurotrophic factor, contributes to the recovery of neurological function, and protects neural cells against injury.
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