GMP Certified Metronidazole Benzoate & Metronidazole

• Customization: Available
• Function: Antibiotic and Antimicrobial Agents
• Certification: GMP
• Model NO.: MTD
• Grade Standard: Medicine Grade
• Type: Chemical Reagent
• State: Solid
• Volatile: Not Volatile
• GMP: Available
• Transport Package: 25kg/Drum
• Specification: BP/USP
• Trademark: Fraken
• Origin: China
• HS Code: 293329
• Production Capacity: 100mt Per Year

Product Description

Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoas.Metronidazole, taken up by diffusion, is selectively absorbed by  and sensitive . Once taken up by anaerobes, it isnon-enzymatically reduced by reacting with reduced , which is generated by pyruvate oxido-reductase. This reduction causes the production of toxic products to anaerobic cells, and allows for selective accumulation in anaerobes.The metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria
Specification: 90%
Other name: 2-Methyl-5-nitro-1-imidazoleethanol;(2-Methyl-5-nitro-1-imidazolee;2-(2-methyl-5-nitroimidazol-1-yl)ethanol
CAS NO.: 443-48-1
EINECS NO.: 207-136-1
MF: C6H9N3O3
MW: 171.15
InChI: 1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
Melting point: 159-163ºC
Water solubility: <0.1G/100MLAT20ºC

Specification:

Test	Specification
Identification	IR
Melting point	159-1630C
Loss on drying	0.5% MAX
Residue on ignition	0.1% MAX
Heavy metals	20ppm MAX
Appearance of solution	Suspension II and solution GY6
Impurity	0.1% MAX
Total impurity	0.2% MAX
Disregard limited	0.01% MAX
Specific absorbance	365-395
Assay	99.0-101.0%

 
Note:
During the period of vaccination or serious defects of the immune function, the drug is banned.
 
Metronidazole Benzoate
Synonyms: benzoylmetronidazole ; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
Molecular Formula: C13H13N3O4
Molecular Weight: 275.26
CAS: 13182-89-3
EINECS: 236-131-7
Standars: BP2007/USP30

Specification

Items	Standards	Results
Appearance	a white or yellowish crystalline powder	Conforms
Solubility	Slightly solube in water, in acetone, in alcohol and in methylene, chloride	Conforms
Identification c), a),b)	c)  infrared a)      Melting point 159-163°c b)      Specific absorbance 365-395	a) 160.5-160.8°c b) 375
Loss on drying	≤0.5%	0.20%
Residue on ignition	≤0.1%	0.03%
Heavy Metal	≤20PPM	<20PPM
Particle size	40-60MESH	COMPLY
Residual solvents	Ethanediol≤620PPM	≤620PPM
Appearance of solution	SUSPENSION AND SOLUTION GY6	COMPLY
Related substance	Single Impurity≤0.1%	0.054%
	Total impurity≤0.2%	0.090%
	Disregard limited≤0.01%	pass
Assay	99.0%-101.0% C6H9N3O3	99.60%C6H9N3O3