D-Glucuronolactone
Chemical name: D-glucuronic acid-of γ -lactone
CASNO: 32449-92-6
Molecular formula: C6H8O6
Molecular Weight: 176.12
| Appearance |
white crystalline powder |
| Melting point |
170-176 o C |
| Specific rotation |
+18.0 o +20.0 o |
| Loss on dry |
≤0.5% |
| Residue on ignition |
≤0.1% |
| Assay |
C6H8O6 (dry) 98.5-102.0% |
Glucuronolactone is a medical raw material, it will be catalyzed as glucuronic acid by enzyme in our body, after combine with metabolites, tonic substances or drugs in liver and intestinal tract, non-toxic glucuronic acid combination will be generated and urinated. Meanwhile, glucuronolactone decrease activity of liver amylase, prevent glycogenolysis, increase content of glycogen, reduce storage of fattiness. Glucuronolactone also can be used for hepatitis, hepatocirrhosis, food and drug poisoning. It is the adjuvant drug of arthritis, rheumatoid arthritis.
Glucuronolactone is also food additive, which is widely used in health foods and functional beverages. It has effect of regulating immune function, moistening skin, anti-aging, improving oxygen to the brain and help recover from fatigue, etc.
Minoxidil
Alias: Minoxidil, 6-(1-piperidine)-2, 4-diflooronitrohenzene pyrimidine diamines-3-oxide
CAS No.: 38304-91-5
Molecular formula: C9H15N5O
Molecular weight: 209.25
Function: Minoxidil is commonly use for hair loss.
Specification:
| Items |
Standard USP37 |
Results |
| Character |
White or almost white crystalline powder |
White crystalline powder |
| Identification: |
Positive |
Positive |
| Residue on ignition |
≤0.5% |
0.05% |
| Heavy metals |
NMT 20ppm |
4ppm |
| Sulphated ash |
NMT 0.1% |
0.04% |
| Loss on drying |
NMT 0.5% |
0.13% |
| Total impurities |
NMT 1.5% |
Conforms |
| Residual solvents |
Methanol NMT 3000ppm |
Conforms |
| Ethanol NMT 5000ppm |
Conforms |
| Ethyl acetate NMT 5000ppm |
Conforms |
| Assay(HPLC) |
97%-103% |
99.52% |
Minoxidil is an antihypertensive vasodilator medication. It also slows or stops hair loss and promotes hair regrowth. Now off-patent, it is available over-the-counter for the treatment of androgenic alopecia. Widely used for the treatment of hair loss, it has been proven clinically effective in both the prevention of loss and in establishing varying degrees of hair re-growth in males and females suffering pattern baldness. Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth.
Minoxidil sulfate salt
Alias: Minoxidil sulfate salt
CAS No.: 83701-22-8
Molecular formula: C9H15N5O4S
Molecular weight: 289.31
Function: Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µ M) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.
D-Glucuronolactone: CP2005
Sodium glucuronolactone: CP2005
Minoxidil: USP24
Minoxidil Sulphate
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